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Cardioprotective effects of aspirin compromised by other NSAIDs

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7414.520 (Published 04 September 2003) Cite this as: BMJ 2003;327:520
  1. Scott Gottlieb
  1. New York

    People who take other painkillers containing non-steroidal anti-inflammatory drugs (NSAIDs) along with aspirin could be losing the cardioprotective benefits of the aspirin, new research has suggested.

    The NSAIDs, which work by interfering with the two enzymes COX 1 and COX 2, seem to compete against aspirin when the two types of drug are taken together, said Dr Tobias Kurth, lead author of the study, which was published online in advance of the print version of Circulation (http://circ.ahajournals.org). …

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