BMJ 1995;311:1325-1327 (18 November)

Papers

Psychosis with good prognosis in Afro-Caribbean people now living in the United Kingdom

Kwame McKenzie, clinical research fellow,a Jim van Os, MRC training fellow,a Tom Fahy, consultant psychiatrist,b Peter Jones, senior lecturer,a Ian Harvey, consultant psychiatrist,c Brian Toone, consultant psychiatrist,b Robin Murray, professor a

a Department of Psychological Medicine, Kings College Hospital London and the Institute of Psychiatry, London SE5 8AF, b Maudsley Hospital, London SE5 8AZ, c Towers Hospital, Leicester LE5 0TD

Correspondence to: Dr K McKenzie, Brixton Community Care Project, Maudsley Hospital, 103 Denmark Hill, London SE5 8AZ.

Abstract

Objectives: To compare the course and outcome of psychotic illness in a group of Afro-Caribbean patients resident in the United Kingdom and a group of white British patients.
Design: Cohort study of consecutive admissions followed up for four years.
Subjects: 113 patients with psychotic illness of recent onset admitted to two south London hospitals.
Main outcome measures: Course of illness, history of self harm, social disability, treatment received, and hospital use adjusted for socioeconomic origin.
Results: The Afro-Caribbean group spent more time in a recovered state during the follow up period (adjusted odds ratio 5.0; 95% confidence interval 1.7 to 14.5), were less likely to have had a continuous illness (0.3; 0.1 to 0.8), were less at risk of self harm (0.2; 0.1 to 0.8), and were less likely to have been prescribed antidepressant treatment (0.3; 0.1 to 0.9). There were no differences in hospital use, but the Afro-Caribbean group had more involuntary admissions (8.9; 2.1 to 35.6) and more imprisonments over the follow up period (9.2; 1.6 to 52.3).
Conclusions: Afro-Caribbean patients in the United Kingdom have a better outcome after psychiatric illness than do white people. The combination of high incidence and more benign course of illness of psychotic illness in this group may be due, at least in part, to a greater exposure to precipitants in the social environment.

Key messages

  • Key messages

  • Both the increased incidence and the better prognosis of psychosis in people of Caribbean origin may be due, at least in part, to excess exposure to social precipitants

  • The four year risk of self harm in people of Caribbean origin with psychosis is lower than in white people, but the increasing incidence of self harm in the wider Afro-Caribbean population may lead to an attenuation of the protective effect conferred by ethnic group

  • Being of lower social class is associated with progressively more deteriorated course of illness in the functional psychoses


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