Abdominal obesity and the "hypertriglyceridaemic waist" phenotype

doi:10.1136/bmj.322.7288.687

BMJ 2001;322:687-689 ( 24 March )

Editorials

Abdominal obesity and the "hypertriglyceridaemic waist" phenotype

It's probably not yet time to implement screening

Clinical review p 716

The first 150 words of the full text of this article appear below.

Generalised obesity, measured by body mass index (weight (kg)/(height (m)²)), is one of the major causes of ill health in western society.However, abdominal obesity $---$ which is closely associated with intra-abdominalfat and measured either by waist circumference or waist:hip ratio $---$ predictssubsequent coronary artery disease better than body mass index.¹Furthermore, obesity, particularly abdominal obesity, is associatedwith insulin resistance, and predicts the development of type2 diabetes. ² ³ On p 716 Després et al argue that waist circumferenceshould be routinely measured in primary care and used to identifypeople with abdominal obesity, on whom efforts to reduce obesityshould be targeted.⁴

High waist measurement may be useful for screening since (a) height contributes little to the variance, (b) it accuratelypredicts obesity and high waist:hip ratio,⁵ and (c) it predictstraditional coronary artery disease risk factors.⁵ High waistand fasting triglyceride measurements $---$ the hypertriglyceridaemicwaist $---$ is a marker . . . [Full text of this article]

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Treatment of obesity: need to focus on high risk abdominally obese patients: Jean-Pierre Després, Isabelle Lemieux, and Denis Prud'homme
BMJ 2001 322: 716-720. [Extract] [Full Text] [PDF]

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Esmaillzadeh, A., Mirmiran, P., Azizi, F. (2005). Whole-grain intake and the prevalence of hypertriglyceridemic waist phenotype in Tehranian adults. Am. J. Clin. Nutr. 81: 55-63 [Abstract] [Full text]
Visscher, T. L. S., Rissanen, A., Seidell, J. C., Heliovaara, M., Knekt, P., Reunanen, A., Aromaa, A. (2004). Obesity and Unhealthy Life-Years in Adult Finns: An Empirical Approach. Arch Intern Med 164: 1413-1420 [Abstract] [Full text]

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