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New drugs can help to face a growing challenge
| The first 150 words of the full text of this article appear below. |
Nephropathy and renal failure remain a major complication of diabetes. New drugs have been developed, and clinical trials have established improved methods of preventing progression of nephropathy to end stage renal failure, yet the proportion of patients with diabetic nephropathy on chronic dialysis programmes is rising. In the United States diabetes has become the most common cause of end stage renal failure in patients starting dialysis.1 In the United Kingdom the figures are progressively increasing. How has this come about?
There are important differences between type 1 and type 2 diabetes.
Among white patients in the United Kingdom with type 1 diabetes of
15-30 years' duration, fewer than 20% will have established nephropathy.2 This is broadly comparable to other European centres, although surveys in the United States show higher numbers and
data from Sweden show lower numbers.2 The prevalence of nephropathy is higher among patients of Asian or African-Caribbean origin. Although the proportion
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What can you learn from this BMJ paper? Read Leanne Tite's Paper+