Bupropion and telephone support helps smokers quit

doi:10.1136/bmj.328.7437.0-f

BMJ 2004;328 (21 February), doi:10.1136/bmj.328.7437.0-f

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Bupropion and telephone support helps smokers quit

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Question How beneficial is the combination of bupropion andtelephone support to help smokers quit?

Synopsis We know that physician advice and bupropion can eachhelp people quit smoking. This randomised controlled trial (non-blinded)was conducted in a primary care setting and included 1524 smokers.Both minimal and moderate intensity counselling were assessedalong with two dosing regimens of sustained-release bupropion(150 or 300 mg per day). Minimal counselling using the Zybanadvantage plan consisted of one 5-10 minute scripted phone callthe day after the quit date and four progress questionnairesmailed thereafter. Moderate counselling was a telephone supportprogramme based on strategies recommended by the US PreventiveServices Task Force and included five scheduled phone callswith individualised content, mailed materials, and access toa toll-free quit line for one year. Thus, there were four groups:minimal counselling with bupropion 150 mg; moderate counsellingwith bupropion 150 mg; . . . [Full text of this article]