BMJ 2008;336:299 (9 February), doi:10.1136/bmj.39482.496725.DB
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Circumcision of men did not cut HIV transmission to their wives
Bob Roehr
1 Boston
| The first 150 words of the full text of this article appear below. |
Voluntary circumcision of men reduced their acquisition of herpes simplex virus by about 25% and cut in half the rate of ulcerative genital diseases, primarily herpes, among their wives. But disappointingly, among those men who were HIV positive, circumcision did not seem to affect the rate of transmission of HIV to their wives.
The study was part of broad ongoing population research being conducted in the rural Rakai region of Uganda as part of an almost 20 year collaboration between local and US investigators. It was presented this week at the 15th Conference on Retroviruses and Opportunistic Infections.
Three earlier studies conducted in Uganda, Kenya, and South Africa had shown that men who became circumcised reduced their risk of acquiring HIV infection by more than half.
"For us, it stands right up with prevention of mother to child transmission as an intervention that really can work," said the Johns Hopkins
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