Early membrane rupture is a risk factor for group B sepsis

Rupture of membranes before the onset of labour is an additional important risk factor for early onset group B streptococcal sepsis in infants. A case-control study by Oddie and colleagues (p 308) confirmed the well established risk factors: prematurity, intrapartum fever, and premature rupture of membranes. The study found that to prevent or ameliorate three quarters of cases of streptococcal sepsis, 16% of all women in labour would need to be given antibiotics.

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Relevant Article

Risk factors for early onset neonatal group B streptococcal sepsis: case-control study

Sam Oddie and Nicholas D Embleton
BMJ 2002 325: 308. [Abstract] [Full Text] [PDF]