BMJ  2003;327 (16 August), doi:10.1136/bmj.327.7411.0

Use of NSAIDs in pregnancy increases risk of miscarriage

Using non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, during pregnancy increases the risk of miscarriage. In a prospective cohort study of 1055 pregnant women in the Kaiser Permanente population of northern California, Li and colleagues (p 368) found that the use of NSAIDs or aspirin around the time of conception or during pregnancy increased the risk of miscarriage by 80%. Using acetaminophen (paracetamol) did not increase the risk of miscarriage.

Credit: TRENO/PHOTONICA


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Relevant Article

Exposure to non-steroidal anti-inflammatory drugs during pregnancy and risk of miscarriage: population based cohort study
De-Kun Li, Liyan Liu, and Roxana Odouli
BMJ 2003 327: 368. [Abstract] [Full Text] [PDF]

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