Letters
Conundrum of the HOPE study
Authors' reply
BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7416.682 (Published 18 September 2003) Cite this as: BMJ 2003;327:682- J Bosch, assistant clinical professor (jackie@ccc.mcmaster.ca),
- S Yusuf, professor of medicine
- McMaster University, 237 Barton Street East, Hamilton, ON, Canada L8L 2X2
EDITOR–Taylor speculates that the reason that the HOPE (heart outcomes prevention evaluation) study did not show a significant relation between blood pressure and outcome was because ramipril was taken at bedtime.1
We believe that this assertion is incorrect for several reasons.
Firstly, the population studied in the paper by Svensson et al differed substantially from the overall HOPE population.2 This substudy focused on 38 patients who had peripheral arterial disease …
Log in
Log in using your username and password
Log in through your institution
Subscribe from £173 *
Subscribe and get access to all BMJ articles, and much more.
* For online subscription
Access this article for 1 day for:
£38 / $45 / €42 (excludes VAT)
You can download a PDF version for your personal record.