BMJ  2003;327 (1 November), doi:10.1136/bmj.327.7422.0-c

Multidrug therapy has reduced death and illness in HIV infected children

Since the introduction of potent anti-HIV drugs in 1997 the risk of death, progression to AIDS, and hospital admission in children with perinatally acquired HIV have decreased substantially in the United Kingdom and Ireland. Gibb and colleagues (p 1019) report results from the national study of HIV in pregnancy and childhood (NSHPC) and the collaborative HIV paediatric study (CHIPS) cohort on nearly 1000 children under clinical care between the late 1980s and 2002. Since the mid-1990s the transmission of HIV from mothers to babies has reduced, but the number of children under care is increasing and they are becoming older. The total number of admissions has fallen by only a quarter since 1996, which has implications for service development.

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Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland

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BMJ 2003 327: 1019. [Abstract] [Full Text] [PDF]