Antibiotics are no better than placebo for symptoms of sinusitis

Question Is co-amoxiclav effective in treating acute sinusitis diagnosed in general practice?

Synopsis Sinusitis is a tricky diagnosis; just distinguishing sinus infection from rhinitis is difficult. Moreover, a good proportion of the patients who have sinusitis have a viral infection. This randomised controlled trial (double blind) study evaluated the role of antibiotics in 252 adults with a clinical diagnosis of rhinosinusitis. The patients had a history of repeated purulent …