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BMJ 2004;328:E294 (17 April), doi:10.1136/bmj.328.7445.E294
Some advice for fishermen (and women) who suffer the agony of getting fishhooks stuck in fingers and arms ( Trout Fisherman August 2003: 32). Rather than pushing the hook through, cutting the barb off, and pulling the shank out, you are advised to let someone else pass a string around the hook; while holding both ends in their hand, they should press down on the hook to release the barb, then pull on the string ends to remove the hook. Removal from other body parts should be referred to hospital.
Minerva enjoyed reading about thyroid nodules, and what they're all about, in a commentary entitled "Thyroid incidentaloma: the ignorant in pursuit of the impalpable." Should they be systematically biopsied and removed, or can some just be left alone? Ultrasound has brought the issue of occult thyroid carcinoma into the clinical domain of the incidental finding. All this is reminiscent, of course, of the prostate and the cervix, and what informed consent to investigate actually means ( Clinical Endocrinology 2004;60: 18-20[CrossRef][Medline]).
Neonatal jaundice, caused by an accumulation of bilirubin, is usually treated with phototherapy, but drug treatment might be the way of the future. A Chinese herbal remedy for jaundice (Yin Zhi Huang), which is taken in the form of an herbal tea, is now known to activate a liver receptor that enhances the clearance of bilirubin ( Journal of Clinical Investigation 2004;113: 23-25[CrossRef][ISI][Medline]).
Emergency departments have to schedule cover 24 hours a day, seven days a week. Different shifts are perceived to offer different levels of stress, both personally and professionally. A two year study of scheduling at one American teaching hospital found that despite scheduling changes designed to improve equality, no improvement in perceived stress could be identified. The authors say the next step is to identify other predictors of stress, fairness, and job satisfaction within emergency medicine faculties ( Academic Emergency Medicine 2004;11: 111-114[Medline]).
Inflammatory mechanisms have been implicated in the pathogenesis of Alzheimer's disease, possibly via the cyclo-oxygenase-2 enzyme. But a one year randomized, blinded controlled trial of a selective COX-2 inhibitor (rofecoxib) failed to show that it slowed the progression of the disease. Possibly the disease process is too advanced to modify in people with established dementia, but it may be that the role of COX-2 is simply not as important as has been thought (
Neurology
2004;62: 66-71
People who perceive their psychosocial work environment negatively have more complaints about the indoor environment and attribute more symptoms to the indoor air, according to a questionnaire survey of over 11 000 employees (
Occupational and Environmental Medicine
2004;61: 143-149
Fresh data from the Baltimore longitudinal study of aging seem to indicate that calculated free testosterone concentrations are lower in men who develop Alzheimer's disease and that the difference occurs before diagnosis. The obvious question is, do higher endogenous free testosterone concentrations protect against the disease in older men? (
Neurology
2004;62: 188-193
An international round-up of the latest cremation rates around the world shows that Japan has the highest rate per population (99.5%) and Cuba has the lowest (0.5%). Great Britain comes in at 71.9%, and the United States at just 27.8%. The variation may depend on several factors, including geographical space, cultural beliefs, and the number of crematoriums available. Japan has 1600, while Cuba reports just one ( Pharos International Winter 2003: 24-36).
Getting people to cough while you're taking blood from them is a neat little trick that acts as a good pain reliever. In 20 healthy male volunteers taking part in a randomized crossover study the reported intensity of pain they experienced was significantly lower when they coughed, whereas other variables such as hand withdrawal, palm sweating, blood pressure, heart rate, and serum glucose concentrations changed insignificantly. The mechanism is unknown (
Anesthesia and Analgesia
2004;98: 343-345
Despite the popularity of optimism among some health care workers, having a positive attitude didn't improve the survival rate of 179 patients with a common form of lung cancer. Reporting a paper published in the latest edition of Cancer, one of the researchers said, "We should question whether it is valuable to encourage optimism if it results in the patient concealing his or her distress in the misguided belief that this will afford survival benefits" ( Tallahassee Democrat, February 9, 2004).
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Soccer injuries seem to beget more injuries, according to a prospective cohort study from Iceland reported in the
American Journal of Sports Medicine ( 2004;32[suppl]: 5S-16S)
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What can you learn from this BMJ paper? Read Leanne Tite's Paper+