Long term budesonide does not affect adrenal function in children

Question Does the use of chronic inhaled corticosteroids affect adrenal function in children?

Synopsis Uncontrolled (for example, cross sectional or retrospective) studies have found that chronic inhaled corticosteroid use in children may affect hypothalamic-pituitary-adrenal axis function. These authors evaluated this effect with a randomised controlled trial (non-blinded) in 63 children with mild to moderate asthma who received standard doses of budesonide (400 µg/day; …