BMJ  2004;329 (16 October), doi:10.1136/bmj.329.7471.0

Depression accompanies cognitive decline

People with cognitive impairment are more likely to become depressed, but depression does not increase the risk of developing cognitive impairment. Following up 500 Dutch residents aged 85, Vinkers and colleagues (p 881) found that after four years depressive symptoms had increased more quickly in those with poorer attention, immediate recall, and delayed recall at baseline. Having symptoms of depression was not related to accelerated cognitive decline.

Credit: PHOTOALTO/PHOTONICA


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Temporal relation between depression and cognitive impairment in old age: prospective population based study
David J Vinkers, Jacobijn Gussekloo, Max L Stek, Rudi G J Westendorp, and Roos C van der Mast
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