Intended for healthcare professionals

The Polymeal: a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by more than 75%

Oscar H Franco, Luc Bonneux, Chris de Laet, Anna Peeters, Ewout W Steyerberg, Johan P Mackenbach
Table 1

Effect of ingredients of Polymeal in reducing risk of cardiovascular disease

IngredientsPercentage reduction (95% CI) in risk of CVDSource
Wine (150 ml/day)32 (23 to 41)Di Castelnuovo et al (MA)6
Fish (114 g four times/week)14 (8 to 19)Whelton et al (MA)7
Dark chocolate (100 g/day)21 (14 to 27)Taubert et al (RCT)8
Fruit and vegetables (400 g/day)21 (14 to 27)John et al (RCT)10
Garlic (2.7 g/day)25 (21 to 27)Ackermann et al (MA)11
Almonds (68 g/day)12.5 (10.5 to 13.5)Jenkins et al (RCT),15 Sabate et al (RCT)16
Combined effect76 (63 to 84)
  • CVD=cardiovascular disease; MA=meta-analysis; RCT=randomised controlled trial.