BMJ  2005;330 (12 February), doi:10.1136/bmj.330.7487.0

HRT is associated with increased risk of stroke

Hormone replacement therapy (HRT) does not protect postmenopausal women from stroke, but rather increases the risk, particularly of ischaemic stroke. On page 342, Bath and Gray report the results of a meta-analysis of 28 randomised controlled trials with 39 769 participants. Hormone replacement therapy significantly increased the risk of total stroke, non-fatal stroke, stroke leading to death or disability, and ischaemic stroke and was associated with a trend to more fatal stroke. They found no evidence of the association with haemorrhagic stroke or transient ischaemic attack.

Credit: SHEILA TERRY/SPL


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

Relevant Article

Association between hormone replacement therapy and subsequent stroke: a meta-analysis
Philip M W Bath and Laura J Gray
BMJ 2005 330: 342. [Abstract] [Full Text] [PDF]

Access all current jobs at BMJ Group
Whats new online at Student BMJ
Listen to the latest BMJ Interview