BMJ  2005;330 (19 February), doi:10.1136/bmj.330.7488.0-f

Locked-in syndrome

In the locked-in syndrome, which is caused by damage to the ventral pons and leaves the patient with quadriplegia, anarthria, and preserved consciousness, the 10 year survival rate is as high as 80%. This week's clinical review by Smith and Delargy (p 406) summarises what is known about the clinical features, classification, diagnosis, management, and prognosis of patients with locked-in syndrome. The authors emphasise the need for early rehabilitation management, which can significantly improve the quality of life of these patients and their carers.

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