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BMJ 2005;330:E354 (14 May), doi:10.1136/bmj.330.7500.E354
Following is an edited excerpt from one of the Rapid Responses generated by this article, all of which can be read in their entirety at http://bmj.bmjjournals.com/cgi/eletters/330/7489/452#98052.Editor
The patient population studied were hospital out-patients. It is not stated how they were selected to be seen at the hospital. In UK practice most would have been referred by their general practitioners, and therefore be a selected group with at least a suspicion of significant pathology. Large numbers of patients with isolated chest pain may have been filtered out prior to presentation at the hospitals on the grounds that they have `good evidence' of musculoskeletal chest pain as evidenced by localized pain and tenderness without other significant signs and symptoms.
If 20% of all patients in UK general practice presenting with isolated chest pain and tenderness have pulmonary embolism I suggest there may be a massive under diagnosis of this condition and that it warrants further study in a primary care setting.
Richard James, general practitioner
Falmouth Health Centre, TR11 4ED, UK
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