What works for malaria

doi:10.1136/bmj.331.7519.0-a

BMJ 2005;331 (1 October), doi:10.1136/bmj.331.7519.0-a

What works for malaria

Guidelines for treating children with uncomplicated malariachanged in Zambia in 2002 in line with the best available evidence,but the change has not yet translated into adequate use at thepoint of care. A cross sectional study by Zurovac and colleagues(p 734) shows how artemether-lumefantrine, which should be thefirst choice of treatment for children weighing 10 kg or more,is not being prescribed even when available.

Credit: GIACOMO PIROZZI/PANOS

In a cluster randomised trial, Chandramohan and colleagues (p 727)showed that sulfadoxine-pyrimethamine can prevent malariaand anaemia in infants up to 15 months old. These children mayalso have a higher risk of high parasite density malaria aftertreatment is stopped, however.

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Cluster randomised trial of intermittent preventive treatment for malaria in infants in area of high, seasonal transmission in Ghana: Daniel Chandramohan, Seth Owusu-Agyei, Ilona Carneiro, Timothy Awine, Kwame Amponsa-Achiano, Nathan Mensah, Shabbar Jaffar, Rita Baiden, Abraham Hodgson, Fred Binka, and Brian Greenwood
BMJ 2005 331: 727-733. [Abstract] [Full Text] [PDF]

Treatment of paediatric malaria during a period of drug transition to artemether-lumefantrine in Zambia: cross sectional study: Dejan Zurovac, Mickey Ndhlovu, Alexander K Rowe, Davidson H Hamer, Donald M Thea, and Robert W Snow
BMJ 2005 331: 734. [Abstract] [Full Text] [PDF]