The influence of screening on the incidence of ruptured abdominal aortic aneurysms

J Vasc Surg. 1999 Aug;30(2):203-8. doi: 10.1016/s0741-5214(99)70129-1.

Abstract

Purpose: The purpose of this study was to estimate the influence of a screening program on the incidence and mortality of ruptured abdominal aortic aneurysms (RAAAs).

Methods: The effects of screening on the incidence and death rate of RAAAs were investigated with a stepped wedge study design. RAAAs that occurred in the Huntingdon district were traced with an examination of all hospital records and community postmortem records.

Results: During the 5-year period from 1991 to 1996, 78 RAAAs occurred in the Huntingdon district: 62 in men and 16 in women. Eleven of the 62 men with RAAAs had been invited for screening. The incidence of RAAA in the invited group was 3.7 per 10,000 person-years (py; 95% confidence interval [CI], 1.5 - 7.3). In the noninvited group, the incidence was 7.3 per 10,000 py (95% CI, 5.3. - 9.2), a rate ratio of 0.51 (95% CI, 0.26 - 0.97). The mortality of rAAAs in the invited group was 3.0 per 10, 000 py (95% CI, 1.4 - 5.4) as compared with 5.4 per 10,000 py in the noninvited group (95% CI, 3.9 - 7.3), resulting in a rate ratio of 0. 55 (95% CI, 0.26 - 1.15).

Conclusion: Screening for asymptomatic AAAs can reduce the incidence rate of RAAAs by 49% (95% CI, 3% - 74%).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aneurysm, Ruptured / diagnosis
  • Aneurysm, Ruptured / epidemiology*
  • Aneurysm, Ruptured / mortality
  • Aortic Aneurysm, Abdominal / diagnosis
  • Aortic Aneurysm, Abdominal / epidemiology*
  • Aortic Aneurysm, Abdominal / mortality
  • Family Practice
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Mass Screening
  • Middle Aged
  • Prevalence
  • Time Factors
  • United Kingdom / epidemiology