A study of three preparations in the treatment of otitis externa

J Laryngol Otol. 1987 Jun;101(6):533-5. doi: 10.1017/s0022215100102178.

Abstract

Twenty-seven patients with an initial diagnosis of otitis externa, untreated for the previous 2 weeks, were treated with weekly aural suction toilet and a choice of three topical drops. Two contained combinations of antibiotics and steroids, one of which also contained an anti-fungal agent. The third was boric acid in spirit. The patients were assessed at weekly intervals until a remission was established. From this study it would appear that antibiotic-based drops confer no real advantage over boric acid in spirit.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Administration, Topical
  • Boric Acids / administration & dosage*
  • Clinical Trials as Topic
  • Double-Blind Method
  • Drug Combinations / administration & dosage
  • Econazole / administration & dosage
  • Fluocinolone Acetonide / administration & dosage*
  • Humans
  • Hydrocortisone / administration & dosage*
  • Neomycin / administration & dosage*
  • Otitis Externa / drug therapy*
  • Polymyxin B / administration & dosage*
  • Polymyxins / administration & dosage*
  • Random Allocation

Substances

  • Boric Acids
  • Drug Combinations
  • Polymyxins
  • hydrocortisone, neomycin, polymyxin B drug combination
  • Fluocinolone Acetonide
  • Econazole
  • Neomycin
  • Polymyxin B
  • boric acid
  • Hydrocortisone