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Accordingly, high fasting serum glucose concentrations and diabetes are
associated with increased risk of death from several cancers (1). However,
not all diabetics will surely die of cancer! The same remark is also valid
about obesity. I agree, therefore, “partially” with those authors, who
state that both diabetes and obesity are primary risk factors for
malignancies.
Unfortunately, all these authors around the world continue
to overlooke or ignore the real reason of cancer occurrence, we can now
recognize at the bed-side in a “quantitative” way, exclusively in subjects
affected by "Oncological Terrain" (2- 6) (See website, HONCode Id., N°
233736 www.semeioticabiofisica.it ).
In fact, I demonstrated without any doubt that a serious, fundamental,
mitochondria-dependent, and inherited “conditio sine qua non” for all
cancers does really exist. In addition, there is something more to be
carefully considered from pathogenetic view-point, doctors have ignored or
overlooked until now, although it plays a pivotal role in cancer primary
prevention.
In fact, because a congenital functional mitochondrial cytopathology is
overlooked, fundamental basis of the most frequent and dangerous human
disorders, including malignancy, all current clinical research and
statements are fundamentally biased: i.e., Oncological Terrain, based on
Congenital Acidosic Enzyme-Metabolic Histangiopathy account for the reason
that there is the relation between either obesity or diabetes, on the one
hand, and malignancy, on the other hand (2-6). As a matter of fact, both
environmental risk factors and every drug or substance, like oestrogens,
suggested as a risk factor for cancer, "could" surely influence some human
biological functions and/or bring about different disorders, such as
cancers, but exclusively in relation to both the presence, location, and
intensity of CAEMH, particularly intense in a well-defined biological
system, that consequently provokes the “real cancer” risk, obviously in
presence of Oncological Terrain. Finally, “Oncological Terrain”,
indicating abnormalities of psycho-neuro-endocrino immunological system,
i.e., control system against oncogenesis, can be evaluated "clinically",
i.e., at the bed-side, in a “quantitative”, rapid, reliable, and easy
manner.
1) Mayor S. Raised glucose concentrations and diabetes are associated
with cancer risk
BMJ 2005;330:111 (15 January), doi:10.1136/bmj.330.7483.111
3) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica
condizione necessaria non sufficiente della oncogenesi. XI Congr. Naz.
Soc. It. di Microangiologia e Microcircolaz. Abstracts, pg 38, 28
Settembre-1 Ottobre, Bellagio, 1983
4) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica. X
Congr. Naz. Soc. It. di Microangiologia e Microcircolazione. Atti, 61. 6 -
7 Novembre, Siena , 1981.
5) Stagnaro S., Stagnaro-Neri M. Una patologia mitocondriale ignorata: la
Istangiopatia Congenita Acidosica Enzimo-Metabolica. Gazz. Med. It. -
Arch. Sci. Med. 149, 67 1990.
6) Stagnaro-Neri M., Stagnaro S., Cancro della mammella: prevenzione
primaria e diagnosi Sc. Med. 152, 447 1993
Competing interests:
None declared
Competing interests:
No competing interests
14 January 2005
Sergio Stagnaro
Specialist in Blood. Gastrointestinal, and Metabolic Diseases. Researcher in Biophysical Semeiotics.
Via Eraasmo Piaggio 23/8 16037 Riva Trigoso (Genova) Italy
Type 2 Diabetes, Obesity, Oncological Terrain, and Cancer.
Sir,
Accordingly, high fasting serum glucose concentrations and diabetes are
associated with increased risk of death from several cancers (1). However,
not all diabetics will surely die of cancer! The same remark is also valid
about obesity. I agree, therefore, “partially” with those authors, who
state that both diabetes and obesity are primary risk factors for
malignancies.
Unfortunately, all these authors around the world continue
to overlooke or ignore the real reason of cancer occurrence, we can now
recognize at the bed-side in a “quantitative” way, exclusively in subjects
affected by "Oncological Terrain" (2- 6) (See website, HONCode Id., N°
233736 www.semeioticabiofisica.it ).
In fact, I demonstrated without any doubt that a serious, fundamental,
mitochondria-dependent, and inherited “conditio sine qua non” for all
cancers does really exist. In addition, there is something more to be
carefully considered from pathogenetic view-point, doctors have ignored or
overlooked until now, although it plays a pivotal role in cancer primary
prevention.
In fact, because a congenital functional mitochondrial cytopathology is
overlooked, fundamental basis of the most frequent and dangerous human
disorders, including malignancy, all current clinical research and
statements are fundamentally biased: i.e., Oncological Terrain, based on
Congenital Acidosic Enzyme-Metabolic Histangiopathy account for the reason
that there is the relation between either obesity or diabetes, on the one
hand, and malignancy, on the other hand (2-6). As a matter of fact, both
environmental risk factors and every drug or substance, like oestrogens,
suggested as a risk factor for cancer, "could" surely influence some human
biological functions and/or bring about different disorders, such as
cancers, but exclusively in relation to both the presence, location, and
intensity of CAEMH, particularly intense in a well-defined biological
system, that consequently provokes the “real cancer” risk, obviously in
presence of Oncological Terrain. Finally, “Oncological Terrain”,
indicating abnormalities of psycho-neuro-endocrino immunological system,
i.e., control system against oncogenesis, can be evaluated "clinically",
i.e., at the bed-side, in a “quantitative”, rapid, reliable, and easy
manner.
1) Mayor S. Raised glucose concentrations and diabetes are associated
with cancer risk
BMJ 2005;330:111 (15 January), doi:10.1136/bmj.330.7483.111
2) Stagnaro Sergio, Stagnaro-Neri Marina. Introduzione alla Semeiotica
Biofisica. Il Terreno oncologico”. Travel Factory SRL., Roma, 2004.
http://www.travelfactory.it/semeiotica_biofisica.htm
3) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica
condizione necessaria non sufficiente della oncogenesi. XI Congr. Naz.
Soc. It. di Microangiologia e Microcircolaz. Abstracts, pg 38, 28
Settembre-1 Ottobre, Bellagio, 1983
4) Stagnaro S., Istangiopatia Congenita Acidosica Enzimo-Metabolica. X
Congr. Naz. Soc. It. di Microangiologia e Microcircolazione. Atti, 61. 6 -
7 Novembre, Siena , 1981.
5) Stagnaro S., Stagnaro-Neri M. Una patologia mitocondriale ignorata: la
Istangiopatia Congenita Acidosica Enzimo-Metabolica. Gazz. Med. It. -
Arch. Sci. Med. 149, 67 1990.
6) Stagnaro-Neri M., Stagnaro S., Cancro della mammella: prevenzione
primaria e diagnosi Sc. Med. 152, 447 1993
Competing interests:
None declared
Competing interests: No competing interests